Clinical research in homeopathy: systematic reviews and randomized clinical trials

Silvia Waisse


Background: Systematic reviews and randomized clinical trials (RCT) are considered to have the highest level of evidence. Aim: To perform a descriptive review of systematic reviews and RCT on the effectiveness and efficacy of homeopathy. Methods: Data from the report published by Liga Medicorum Homeopathica Internationalis (LMHI) in 2014 were updated by means on a search conducted in database PubMed. Results: 7 systematic reviews with meta-analysis were located, 6 of them concluded that the effects of homeopathy are not compatible with placebo effect; only 1 systematic review arrived to the opposite conclusion, but was severely criticized due to methodological flaws. A total of 19 RCT were published along the analyzed period; 84.2% had at least one positive outcome. Conclusions: Based on the available evidences of the highest level it is not possible to assert that the effects of homeopathic are exclusively placebo effect. On the opposite, specific effects were detected in several studies.


Homeopathy; Efficacy; Effectiveness; Systematic review; Meta-analysis; Randomized controlled trials

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Direitos autorais 2017 Silvia Waisse

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Este obra está licenciado com uma Licença Creative Commons Atribuição 4.0 Internacional.

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

ISSN: 2175-3105